SKU: 11266624835

Shedding, Haaren

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Description

Shedding, HaarenReduzierter Haarausfall (MC5R) ist ein komplexes genetisches Merkmal, das alle Rassen betreffen kann und epistatische Wechselwirkungen mit FGF5 (Felllnge) und RSPO2 (Fellbeschaffenheit) hat, die ebenfalls die Haarmorphologie bei Hunden beeinflussen. Diese Loci haben aufgrund einer starken knstlichen Selektion fr das Fellphnotyp selektive Sweeps durchlaufen. Die MC5R Proteinsequenz ist evolutionr bei Sugetieren konserviert, und eine bestimmte Mutation

Reduzierter Haarausfall (MC5R) ist ein komplexes genetisches Merkmal, das alle Rassen betreffen kann und epistatische Wechselwirkungen mit FGF5 (Felllänge) und RSPO2 (Fellbeschaffenheit) hat, die ebenfalls die Haarmorphologie bei Hunden beeinflussen. Diese Loci haben aufgrund einer starken künstlichen Selektion für das Fellphänotyp selektive Sweeps durchlaufen. Die MC5R-Proteinsequenz ist evolutionär bei Säugetieren konserviert, und eine bestimmte Mutation verursacht eine konformationale Änderung in der Tertiärstruktur des Proteins, das an der Produktion von Talg beteiligt ist, was die Wasserabweisung und Thermoregulation beeinflusst und zu erhöhtem Haarausfall führen kann. Der Gentest kann das Ausmaß des Haarausfalls bei einem Hund offenbaren, was helfen kann, geeignete Hunde für die Zucht auszuwählen und den Haarausfall zu reduzieren. Da einzelne Gene nur Durchschnittswerte für den Haarausfall liefern, ist es fast notwendig, die Kombination der Gene MC5R und RSPO2 zu testen.

Im Folgenden sind 3 Tabellen aufgeführt, die das Ausmaß des Haarausfalls je nach Genotyp zeigen; die letzte veranschaulicht das Ausmaß des Haarausfalls je nach Genotypkombination von MC5R und RSPO2.

MC5R

Genotyp

Grad des Haarausfalls

SD/SD

Niedrig

SD/N

Moderat

N/N

Hoch

N – Wildtyp-Allel, SD - Variantenallel

Hunde mit einem oder zwei Kopien der Variantenallele verlieren weniger Haare als Hunde ohne Kopien.

RSPO2

Genotyp

Grad des Haarausfalls

F/F

Niedrig

F/N

Moderat

N/N

Hoch

F/F - Fellbeschaffenheit, N/F - Fellbeschaffenheit, N/N - unzureichendes Fell

KOMBINATION VON MC5R UND RSPO2

Genotyp MC5R

Genotyp RSPO2

Grad des Haarausfalls

SD/SD

F/F

0

SD/SD

F/N

1

SD/SD

N/N

2

SD/N

F/F

1

SD/N

F/N

2

SD/N

N/N

3

N/N

F/F

2

N/N

F/N

3

N/N

N/N

4

Grade des Haarausfalls: niedrig 0 < 1 < 2 < 3 < 4 hoch

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SKU: 11266624835

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VeroChi
Birmingham, US
★★★★★ 5
Amazing product for hand eczema
I've been seeing ads for this product for a while and finally decided to try it. I'm so glad I did! It's by far the best hand cream I've found for eczema. It doesn't sting at all, and my hands already look and feel so much better.
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Reviewed in the United States on June 6, 2026
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Parties By The Sea
New York, US
★★★★★ 5
Best Product for Dry Skin!
Yes! This is the BEST product for dry skin I can’t live without it now! I have mild eczema and this is one of the best products that helps. It’s very calming, I sometimes mix it with a coconut oil too and I put it everywhere it makes my skin glow too! My friend was having the same issue and I recommended it to her and she messaged me right away saying it’s the only thing working for her. I also love the bubble bath products from the same company!
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Reviewed in the United States on April 27, 2026
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Aishwarya S
Chelsea, US
★★★★★ 4
Effective but slightly greasy
I purchased this for my brother, who has been suffering from eczema and psoriasis for over a decade, and he's never been able to find a product that works for him for longer than a few weeks. The product had already leaked and wasn't packed properly when it arrived, so the sides of the jar were extremely greasy. Absorption is great - it looks like the skin drinks it right up, if applied nominally. I can't speak to long-term effects yet, but there is an immediate reduction in redness and flakiness. Itching does not subside.
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Reviewed in the United States on May 25, 2026
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Kate
Los Angeles, US
★★★★★ 5
Highly recommend! Lifesaver for sensitive dry eczema
Bought this with their face wash, no regrets. My sensitive, peeling eczema face was getting red and uncomfortable (not to mention peeling no matter what special Derm sample products I tried). This is THICK. A little goes a long way. I pat it into my face and dry eczema patches after using the face wash. It lasts awhile, love that it contains aloe. My redness and literal peeling nose, cheek and chin are 80% better after using 2wks. Immediately felt better with first use. Cannot really use under makeup! This is heavy and a bedtime product.
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Reviewed in the United States on March 29, 2026
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Amye Pitts
Boise, US
★★★★★ 5
It does work!
My child was diagnosed with severe eczema and takes the Dupixent shot once a month. He had to stop it for a month before and a month after in order to take his live MMR vaccine. This cream is the first one we have used the actually works. He will still have to get back on his shots, but for a baby with mild to moderate eczema, this might do the trick! Tried it on myself in a few spots and could tell a difference overnight.
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Reviewed in the United States on June 3, 2026

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