SKU: 8807072931

Designs for Health - ProbioSpore 60caps

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Description

Designs for Health - ProbioSpore 60capsSupport gastrointestinal health with Probiospore Contains 4 billion CFU of Bacillus coagulans (IS2) per capsule Improves bowel regularity Maintains intestinal good flora Vegan friendly Education: Designs for Health ProbioSpore is a unique spore based probiotic containing Bacillus coagulans (UNIQUE IS 2TM) as a single ingredient. Originally named Lactobacillus sporogenes, Bacillus coagulans is a transient, gram positive, lactic acid producing bacteria

  • Support gastrointestinal health with Probiospore
  • Contains 4 billion CFU of Bacillus coagulans (IS2) per capsule
  • Improves bowel regularity
  • Maintains intestinal good flora
  • Vegan friendly

 

Education:

Designs for Health ProbioSpore is a unique spore-based probiotic containing Bacillus coagulans (UNIQUE IS-2TM) as a single ingredient.

Originally named Lactobacillus sporogenes, Bacillus coagulans is a transient, gram-positive, lactic acid-producing bacteria that is protected from stomach acid by a protein-based spore coating. Instead of dying off as a result of coming into contact with stomach acid, the spore coating expands, and B. coagulans begins to germinate as it moves out of the stomach and into the duodenum where the environment is more amenable. Germination occurs between 4-6 hours after ingestion, and around 85-93% of the ingested and germinated probiotic ends up in the intestines. Further to this, its preferred growth temperature is between 35-50°C.  As a result, B. coagulans displays an excellent stability profile at ambient temperatures

Once germination has taken place, B. coagulans proliferates in the distal parts of the small intestine and is able to produce the isomeric form of lactic acid. The isomeric form is unlikely to give rise to metabolic acidosis.

Being a transient and not a colonising probiotic, B. coagulans does not remain in the intestinal tract for long and begins to be excreted via the faeces around seven days after supplementation ceases. Despite such a short period of time of activity in the bowel, B. coagulans affects the microbial colony in that it helps to regulate beneficial flora and inhibit the proliferation of opportunistic bacteria via the production of “bacteriocin-like substances” and short-chain fatty acids (SCFAs). These compounds support the health of the GI lining and provide direct antagonism to microbial pathogens.

Bacillus coagulans and Digestion

B. coagulans is also able to produce several enzymes that assist digestive processes such as nutrient breakdown and absorption. Some of these enzymes include lipase, protease, α-amylase and both α- & β-galactosidase and assist with protein and carbohydrate digestion.2 Absorption is also facilitated as B. coagulans can reduce inflammation of the gut lining and promote the health of the permeable areas of the microvilli.

Bowel Regularity

As well as digestion, B. coagulans has also been found to assist excretion. It produces metabolites such as diacetyl, SCFAs and vitamins, stimulates peristalsis, reduces amine production, reduces bowel transit time, and improves the overall health of the bowel. This in turn helps to improve bowel regularity and reduce toxin build-up.

A randomised, double-blind, placebo-controlled clinical trial performed using the Unique IS-2TM strain on 100 men and women suffering from functional constipation showed that supplementation with B. coagulans at a dose of 2bn CFU daily improved stool frequency, consistency, pain associated with defecation, and feelings of incomplete evacuation.

Pain associated with Irritable Bowel Syndrome

The specific strain Unique IS-2TM has also been the subject of a clinical trial included in a meta-analysis for its effects on medically diagnosed irritable bowel syndrome.

Daily dosing of 2 billion CFU of Unique IS-2TM daily was studied in a randomised, double-blind, placebo-controlled trial involving 108 men and women fulfilling ROME III criteria for irritable bowel syndrome. Reduction of abdominal pain and an increase in spontaneous complete bowel movements were the primary endpoints studied. Bacillus coagulans Unique IS-2TM was able to show more than a 50% pain reduction score in 90.5% of patients, and significantly reduced the total symptom severity score (including symptoms such as bloating, incomplete evacuation, urgency, straining, passage of gas, bowel habit satisfaction and stool consistency) from 26.7 to 10.6 (placebo 26.7 to 21.5) over the course of eight weeks

A meta-analysis picked up this trial as well as 41 others done on a number of different probiotic species and concluded that Bacillus coagulans Unique IS-2TM is able to effectively reduce abdominal pain associated with medical diagnosed irritable bowel syndrome

 

Directions for use

Adults: Take one capsule daily with water or as directed by your health professional.

Prescribing Information: Bacillus coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate the administration of antibiotics and B. coagulans preparations by at least two hours

Allergen Information

  • No added: Gluten, Dairy, Egg, Sesame, Peanuts and Tree Nuts
  • Free From: Artificial Flavours, Artificial Colours, Sulfites,
  • Contains soybean products
  • Vegan Friendly
Pack: 60 Capsules
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SKU: 8807072931

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Aquamac
Houston, US
★★★★★ 5
Soft and cooling
Color: 08 - Sage Green, Size: Queen (20" X 30")
These are great pillowcases. Very soft, comfortable, and they stay cool throughout the night. They fit perfectly and feel really nice against your skin.
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Reviewed in the United States on May 21, 2026
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Ashley Hile
Omaha, US
★★★★★ 4
Sheets are good. Greens don't match
Color: 08 - Sage Green, Size: King (20" X 36"), Color: 08 - Sage Green, Size: King (20" X 36")
I purchased the sage green sheets to go along with another Bedsure comforter, then purchased 2 more pillow cases (because i I like a lot of pillows) and the greens don't exactly match. This doesn't REALLY bother me as I feel like its fine with a little "texture." Sheets feel nice and light and I love the look of it in my room.
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Reviewed in the United States on March 3, 2026
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Apple
Draper, US
★★★★★ 5
Good buy Pillowcases
Color: 08 - Sage Green, Size: King (20" X 36")
I bought these Bedsure king-size pillowcases from Amazon and overall I’m very happy with them. The first thing I noticed was how incredibly soft and smooth the fabric feels. They almost feel silky, which makes them very comfortable to sleep on. When you lay your head down, the material feels cool and gentle on the skin, which I really like. I also appreciate the zipper closure. It keeps the pillow securely inside the case and makes everything look neat and tidy on the bed. The zipper is hidden well and doesn’t feel bulky or uncomfortable. The only small downside is that the pillowcases are so smooth that the pillows can sometimes slide around or even slip off the bed a little. However, that’s really just because the material is so silky. Overall, I would still recommend these pillowcases. They are soft, comfortable, and feel like a nice upgrade compared to regular pillowcases.
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Reviewed in the United States on March 8, 2026
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Amazon Customer
Port Orchard, US
★★★★★ 5
Very nice pillowcases
Color: 06 - Beige, Size: Standard (20" X 26")
These pillowcases are really nice. They're soft and wash well. I really like the pocket on the end. It makes your pillows look nice and neat. The price is good too.
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Reviewed in the United States on May 31, 2026
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ShelbbLC
Phoenix, US
★★★★★ 3
Love the sheets but GOSH THEY STINK
Color: 19 - Forest Green, Size: Queen (20" X 30")
I have the dark green sheets and bought these for extra cases to match. I would give them 5 stars if it weren’t for the fact that they smell absolutely horrible. I am so surprised after reading reviews that more people don’t mention it?! Maybe it’s more prominent in darker colors but I have washed these now 3 different times even with scent beads and still hate the smell. I wish I could accurately describe what it smells like— it’s just not good and for some reason, body heat only exacerbates it and makes the smell even worse and I wake up feeling like a smell like the sheets… which isn’t a good thing. Besides that, I do really enjoy them. They feel great on your skin and I love the color. I wish the smell didn’t kill them so badly for me ☹️
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Reviewed in the United States on June 9, 2026

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