SKU: 3002240269

IGFBP3 Recombinant rabbit mAb (SDT-086-63)

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Description

IGFBP3 Recombinant rabbit mAb (SDT-086-63)Product Specification Host Rabbit Antigen IGFBP3 Synonyms Insulin like growth factor binding protein 3, IBP 3, IGF binding protein 3, IGFBP 3 Immunogen Recombinant Protein Location Secreted Accession P17936 Clone Number SDT 086 63 Antibody Type Rabbit mAb Application WB Reactivity Hu Purification Protein A Concentration 0. 5 mg ml Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA, 0. 03% Proclin 300 Stability & Storage 12 months

Product Specification


Host Rabbit
Antigen IGFBP3
Synonyms Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3
Immunogen Recombinant Protein
Location Secreted
Accession P17936
Clone Number SDT-086-63
Antibody Type Rabbit mAb
Application WB
Reactivity Hu
Purification Protein A
Concentration 0.5 mg/ml
Physical Appearance Liquid
Storage Buffer PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage 12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution


application dilution species
WB 1:1000 null

Background

Insulin-like growth factor-binding protein 3, also known as IGFBP-3, is a protein that in humans is encoded by the IGFBP3 gene. IGFBP-3 is one of six IGF binding proteins. IGFBP-3 was first isolated, characterized, and quantitated in human plasma, in 1986. It has well-documented functions in the circulation, in the extracellular environment, and inside cells. It is the main IGF transport protein in the bloodstream, where it carries the growth factors predominantly in stable complexes that contain the binding protein, either IGF-1 or IGF-2, and a third protein called the acid-labile subunit or ALS. IGFBP-3 levels in human serum are, like IGF-1, dependent on growth hormone (GH); for example, serum IGFBP-3 is increased in acromegaly and low in GH-deficient children. However, IGFBP-3 gene expression in human liver is GH-independent. Because it is stabilized in human serum by forming complexes with IGF-1 and ALS, which are both GH-dependent, serum IGFBP-3 also appears regulated by GH. Its production by some non-hepatic tissues may also be directly GH-regulated. Immunoassays for serum IGFBP-3 are often used as part of the diagnosis of childhood GH-deficiency.
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SKU: 3002240269

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Margaret
Lowell, US
★★★★★ 5
Great shoes for business casual, corporate travel
Size: 8.5, Color: White Full Grain
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Reviewed in the United States on December 30, 2025
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Jocko
Whiting, US
★★★★★ 5
Very Comfortable Shoes
Size: 11, Color: Black Full Grain
Were purchased as a gift and the wearer says they are the most comfortable shoes he has
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Reviewed in the United States on December 28, 2025
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DALIA ALVAREZ
Cuba, US
★★★★★ 5
Great shoes
I like these shoes they are comfortable, and look great. Good quality, it fits to its size.
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Reviewed in the United States on May 19, 2025
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Leonardo Perez
Carnegie, US
★★★★★ 1
Mal presentado
Size: 9, Color: Black Full Grain
Un zapato llego con cosido defectuoso
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Reviewed in the United States on October 29, 2025
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Joe
Pawtucket, US
★★★★★ 5
Comfortable
Size: 11.5, Color: Black Full Grain
Fit great very comfortable
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Reviewed in the United States on October 16, 2025

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