SKU: 3548355507

Biotin Rabbit Anti-Human CD326 Antibody (S-1009-76)

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Description

Biotin Rabbit Anti-Human CD326 Antibody (S-1009-76)Product Specification Host Rabbit Antigen CD326 Synonyms Epithelial cell adhesion molecule; Ep CAM; Adenocarcinoma associated antigen; Cell surface glycoprotein Trop 1; Epithelial cell surface antigen; Epithelial glycoprotein (EGP); Epithelial glycoprotein 314 (EGP314; hEGP314); KS 1 4 antigen; KSA; Major gastrointestinal tumor associated protein GA733 2; Tumor associated calcium signal transducer 1; GA733 2; M1S2; M4S1; MIC18; TACSTD1; TROP1

Product Specification


Host Rabbit
Antigen CD326
Synonyms Epithelial cell adhesion molecule; Ep-CAM; Adenocarcinoma-associated antigen; Cell surface glycoprotein Trop-1; Epithelial cell surface antigen; Epithelial glycoprotein (EGP); Epithelial glycoprotein 314 (EGP314; hEGP314); KS 1/4 antigen; KSA; Major gastrointestinal tumor-associated protein GA733-2; Tumor-associated calcium signal transducer 1; GA733-2; M1S2; M4S1; MIC18; TACSTD1; TROP1
Immunogen Recombinant Protein
Location Cell membrane, Cell junction
Accession P16422
Clone Number S-1009-76
Antibody Type Recombinant mAb
Isotype IgG
Application FCM
Reactivity Hu
Positive Sample HT-29
Purification Protein A
Concentration 0.2 mg/ml
Conjugation Biotin
Physical Appearance Liquid
Storage Buffer

PBS pH7.4, 0.03% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1.25μl per million cells in 100μl volume Hu

Background

Epithelial cell adhesion molecule (EpCAM), also known as CD326 among other names, is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell–cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.

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SKU: 3548355507

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