SKU: 35710129583

LILRB3/CD85a/ILT5 His Tag Protein, Human

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Description

LILRB3/CD85a/ILT5 His Tag Protein, HumanProduct Specification Species Human Accession O75022 Amino Acid Sequence Gly24 Glu443, with C terminal 8*His

Product Specification


Species Human
Accession O75022
Amino Acid Sequence Gly24-Glu443, with C-terminal 8*His GPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRLHKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGPPSTPGLGRYLEGGGSHHHHHHHH
Expression System HEK293
Molecular Weight 60-75kDa (Reducing)
Purity

>95% by SDS-PAGE

Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.

Background

LILRB3 is a member of LILRB family that is restrictively expressed on myeloid cells, including monocytes, neutrophils, eosinophils, and basophils (as well as on in vitro differentiated mast cells and osteoclasts). LILRB3 contains four cytoplasmic ITIM motifs hat may contribute to negative regulation of immune response. Ligation of LILRB3 in human myeloid cells led to inhibition of immune activation. LILRB3 may be an inhibitor of allergic inflammation and autoimmunity. However, the ligand for LILRB3 has not been identified, and the downstream signaling of LILRB3 is unclear. It is noteworthy that LILRBs, including LILRB3, are primate specific.

LILRB3 is also expressed on some myeloid leukemia, B lymphoid leukemia, and myeloma cells. It is reportedly co-expressed with stem cell marker CD34 and with myeloma marker CD138.

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SKU: 35710129583

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4.7 ★★★★★
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Kelsey
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★★★★★ 5
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Reviewed in the United States on May 8, 2026
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TERRIE GILLAND
Carnegie, US
★★★★★ 5
Actually Durable
Color: B) Medium 3" Ball
One of the few "heavy duty" toys that my pittie hasn't destroyed after a couple of weeks. Most of them last two days. She's an absolute beast so I'm confident if she can't destroy it, few dogs can.
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Reviewed in the United States on April 28, 2026
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Cody
Belleville, US
★★★★★ 1
Not for aggressive chewers!
Color: H) Infinity Ring, Color: H) Infinity Ring
Not for aggressive chewers! Done for in about two minutes. I unboxed this and tugged with my Mal for a but then let her have it. Within minutes she had chewed through it. Not worth the money.
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Reviewed in the United States on April 10, 2026
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Nicole Lomonaco
Phoenix, US
★★★★★ 4
Dog ball
Color: A) Small 2.5" Ball
My dog enjoys but smaller than expected
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Reviewed in the United States on May 20, 2026
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Amy
Waukegan, US
★★★★★ 5
Great tough ball
Color: A) Small 2.5" Ball
Great ball for dogs who like to destroy most any ball. Our girl loves this. Yay!!!
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Reviewed in the United States on March 17, 2026

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