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Description
LILRB4/CD85k/ILT3 mFc Chimera Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms Leukocyte immunoglobulin (Ig) like receptor B4,LILRB4, CD85K, ILT3 Amino Acid Sequence Gln22 Glu259, with C terminal Mouse IgG2a Fc
Product Specification
| Species | Cynomolgus |
| Synonyms | Leukocyte immunoglobulin (Ig)-like receptor B4,LILRB4, CD85K, ILT3 |
| Amino Acid Sequence | Gln22-Glu259, with C-terminal Mouse IgG2a Fc YHLDKEGSPAPWDTQNPLEPRNKAKFSIPSMTQHYAGRYRCYYHSHPDWSEDSDPLDLVMTGAYSKPILSVLPSPLVTSGESVTLLCQSQSPMDTFLLFKEGAAHPLPRLRSQHGAQLHWAEFPMGPVTSVHGGTYRCISSRSFSHYLLSRPSDPVELTVLGSLESPSPSPTRSISAAAGPEDQSLMPTGSDPQSGLRRHWEIEGRMDEPRGPTIKPCPPCKCPAPNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPPEEEMTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEKKNWVERNSYSCSVVHEGLHNHHTTKSFSRTPGK |
| Expression System | HEK293 |
| Molecular Weight | 57-74kDa (Reducing) |
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | Mouse Fc Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
Background
Leukocyte immunoglobulin (Ig)-like receptor B4 (LILRB4) is a member of leukocyte Ig-like receptors (LILRs). LILRB4 is encoded in the leukocyte receptor cluster, which is on human chromosome 19q13.4. The structure and function of LILRs are similar to those of other leukocyte receptor cluster receptors, such as killer cell immunoglobulin-like receptors. Leukocyte immunoglobulin-like receptor (LILRB4) is a kind of inhibitory receptor that plays a key role in immune checkpoint pathways. Inhibitory receptors also participate in achieving balance between activating and inhibitory actions to ensure immune responses to pathogens in the immune system. However, they not only protect the host from autoimmune responses, but also preserve peripheral tolerance. LILRB4 also regulates immune responses, and its role in regulating immune responses is mostly controlled by its ligands.
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Exchange/Return Notes
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4.3 ★★★★★
Based on 16 reviews
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Product Reviews
★★★★★ 5
Good toy
Color: Hammer, Size: 7 Inch
Solid value for the $. The hammer seems particularly good, my bigger dogs like to hold it down by the head. I bought a 2nd.
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Reviewed in the United States on March 12, 2026
★★★★★ 5
Skye loves it!
Color: Hammer, Size: 7 Inch
My heavy chewer loves these! I had to get the whole set because come on! Skye steals ALL my husbands tools so when I saw these and saw they’re real wood! (My dog is a wood chewing machine) (ask my deck) anyway these work and keep his teeth off my furniture! 10/10 recommend!
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Reviewed in the United States on March 22, 2026
★★★★★ 1
Unsafe Toy
Color: Pliers, Size: 7 Inch
A waste of money for chewers. Within 10 minutes pieces started breaking off. Unsafe.
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Reviewed in the United States on June 12, 2026
★★★★★ 5
Good toy for tough chewer.
Color: Hammer, Size: 7 Inch
My dog loved this toy. I would purchase again. Was a pretty tough toy, lasted longer than most.
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Reviewed in the United States on March 29, 2026
★★★★★ 5
Durable
Color: Hammer, Size: 7 Inch
Even my monster hasn't been able to chew through these in a few months, and he has destroyed one of the black Kongs in the same time frame.
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Reviewed in the United States on May 24, 2026