SKU: 95881344823

USP14 His Tag Protein, Human

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Description

USP14 His Tag Protein, HumanProduct Specification Species Human Synonyms Ubiquitin carboxyl terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin specific processing protease Accession P54578 Amino Acid Sequence Pro2 Gln494

Product Specification


Species Human
Synonyms Ubiquitin carboxyl-terminal hydrolase 14, Deubiquitinating enzyme 14, Ubiquitin thioesterase 14, Ubiquitin-specific-processing protease
Accession P54578
Amino Acid Sequence

Pro2-Gln494 PLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGNIKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDKKVNQQPNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEESEQGGGSHHHHHHHH

Expression System Baculovirus-InsectCells
Molecular Weight 58kDa (Reducing)
Purity ＞95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Liquid
Storage Buffer 20mM Hepes, 100mM NaCl, 10%Glycerol, 3mMDTT pH8.0
Stability & Storage

·12 months from date of receipt, -20 to -70 °C as supplied.
·1 month, 2 to 8 °C under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.
Reference

Front Pharmacol. 2022 Jan 5:12:801328. J Cell Physiol. 2021 May;236(5):3396-3405. Epub 2020 Nov 1.

Background

Ubiquitin-specific protease 14 (USP14), a deubiquitinating enzyme (DUB), is associated with proteasomes and exerts a dual function in regulating protein degradation. USP14 protects protein substrates from degradation by removing ubiquitin chains from proteasome-bound substrates, whereas promotes protein degradation by activating the proteasome. Increasing evidence have shown that USP14 is involved in several canonical signaling pathways, correlating with cancer, neurodegenerative diseases, autophagy, immune responses, and viral infections. The activity of USP14 is tightly regulated to ensure its function in various cellular processes. Due to its intriguing roles in the stabilization of disease-causing proteins and oncology targets, USP14 has garnered widespread interest as a therapeutic target.

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SKU: 95881344823

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Miss Mousey
New York, US
★★★★★ 5
It’s great and comfy
Color: 17 - Emerald Green, Size: Full
It extremely soft and the all around elastic/ deep pocket are great because my mattress is tall and I roll around like a rotisserie chicken at night, but the sheets don’t come off. It’s fantastic and I’m sure to get more colors of the sheet
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Reviewed in the United States on June 5, 2026
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Oldvtgal
Natrona Heights, US
★★★★★ 5
For soft, sensually awesome sheets- LOOK no more!
Color: 15 - Sage Green, Size: Full
Would give 10 stars if possible! (And this is a nonpaid for review!) When I received the sheets, instantly I knew that I had the right ones, had bought a down comforter close in color as well.. these sheets? The material is strong yet, soft and warm. So so especially soft, and when I make up the bed, ahhh! plus the corners on the fitted, such a cinch to pull over the mattress, even with a topper on the bed! Feels almost spa-like <3 Very comfy, so far in the winter and in 85 degree heat! Soft and easy peasy to care for, too. Washing is a breeze, dry and fold. So far the only thing I can smell on these sheets is my wonderful detergent! Will purchase again. And possibly, again! Thank you!!
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Reviewed in the United States on May 21, 2026
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Kari
New York, US
★★★★★ 5
Fit ✅ Color ✅ Soft ✅
Color: 09 - Brown, Size: King, Color: 09 - Brown, Size: King
Color is exactly as advertised. Feels very soft, fits perfectly. No weird odor and not too warm 🥵. Only downfall I can tell is it seems a bit thin.
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Reviewed in the United States on June 7, 2026
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michele schmitz
Chelsea, US
★★★★★ 3
Very thin. You get what you pay for.
Color: 01 - White, Size: Queen
You get what you pay for. I first noticed the softness which was great. The quality is very thin. They are cool which is great. I have not washed them yet. I would suggest washing them on cool and gentle by themselves. And because they are so thin I would fluff dry for an hour if you have that setting. The two things that damages clothes and sheets, etc. are if you have an agitator in your washer, those ruin clothes and the heat you choose for the fabric you’re drying I always wash my clothes on cold. I do not have an agitator anymore and on delicate and thin fabrics, I use fluff dry. It is cool, but it will dry, especially if it is thin and I’ve had to dry my fine delicates a little bit longer on fluff that way they don’t shrink because the shrinking comes in from the heat from the dryer so keep that in mind another good thing to remember if you got white sheets like I did is that when you use your detergent add a little bit of borax or laundry booster and they will help get them clean and sparkly white. I am on the fence about whether I would recommend this or not if you’re tight on money and you take good care of them I would recommend that you get them. I’m a linen freak and I buy mostly expensive sheets and I thought I would try this out so that’s where I’m at.
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Reviewed in the United States on May 26, 2026
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Alba
Grantham, US
★★★★★ 5
Love it
Size: Queen, Color: Dark Heather Grey
I absolutely love it!!! So comfortable, soft. Not too warm not cold it’s just perfect. Will definitely be buying more. Quality is great, no wrinkles, looks great, washed how instructed no issues :) . True size that’s what another plus. It’s definitely worth the value for your money.
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Reviewed in the United States on January 14, 2026

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