SKU: 22512354074

Tri-Fortify® Watermelon Box of 20 Individual Serving Packets. *

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Description

Tri-Fortify® Watermelon Box of 20 Individual Serving Packets. *Clinically Researched Liposomal Glutathione Tri Fortify Liposomal Glutathione is a clinically researched liposomal glutathione in a delicious oral delivery system, providing superior cellular absorption. Tri Fortify is backed by peer reviewed, published clinical research. Furthermore, Tri Fortify overcomes the common shortcomings of other glutathione supplements. We spent two years developing our unique manufacturing process to create the best

Clinically Researched Liposomal Glutathione

Tri-Fortify® Liposomal Glutathione is a clinically researched liposomal glutathione in a delicious oral delivery system, providing superior cellular absorption.

Tri-Fortify® is backed by peer-reviewed, published clinical research. Furthermore, Tri-Fortify® overcomes the common shortcomings of other glutathione supplements. We spent two years developing our unique manufacturing process to create the best liposomal glutathione supplement. Our objectives were to:

  • Provide superior intracellular absorption
  • Create a heat-stable product that does not require refrigeration.  (After subjecting Tri-Fortify® to 104°F and 75% humidity for 90 consecutive days, it still exceeded label claims)
  • Develop a flavor that both children and adults could enjoy by eliminating the strong sulfur smell and taste associated with other glutathione products.

*This product may take longer to ship out*

Tri-Fortify® Liposomal Glutathione: One Product. Two Flavors. Three Mechanisms of action.

  • Bolsters antioxidant action*
  • Promotes detoxification*
  • Fortifies the immune system*

What’s liposomal glutathione?

Glutathione has been dubbed the “master antioxidant” for its ability to recycle other antioxidants in the body. Glutathione’s importance in supporting overall health is documented in numerous peer-reviewed studies. These benefits include supporting healthy detoxification, promoting a healthy immune system, and moderating oxidative stress levels.*  Glutathione is also essential for brain function, metabolic and biochemical reactions such as DNA synthesis and repair, and is critical in supporting the health of organs such as the lungs and kidneys.*

Not all glutathione products are created equal

Typical glutathione capsule benefits are minimal. Absorption is fundamentally difficult due to its naturally limited bioavailability. Its unstable nature means it is often oxidized during the manufacturing processes or when exposed to heat during storage. Simply put, most glutathione products do not effectively absorb into the cells. For glutathione to be effectively utilized by the body, it must be easily absorbed.

Tri-Fortify® – The superior liposomal glutathione

To ensure maximum absorption of glutathione, a liposomal solution is required. Liposomal glutathione enables greater cellular absorption in all areas of the body. Glutathione is produced by every cell; however, due to environmental stressors and toxins, the body can benefit from additional cellular support.

Peer-reviewed published clinical research on Tri-Fortify®

Penn State University conducted an 4-week human study using Tri-Fortify® Liposomal Glutathione to assess changes in intracellular glutathione absorption (not just plasma levels).  Researchers also looked at natural killer cell function and oxidative stress markers.

The study showed significant increases in intracellular glutathione levels after just 2 weeks of use, as well as demonstrating its ability to support healthy NK cell function and oxidative stress levels.*

Key insights:

Bolsters Antioxidant Action*

Glutathione is a tri-peptide composed of the three amino acids L-glutamic acid, L-cysteine, and L-glycine.

  • Known as the master antioxidant because it recycles other antioxidants, such as vitamins C and E.* This is why Tri-Fortify® has so much synergy with liposomal vitamin C
  • Because glutathione exists within cells, it is in a prime position to neutralize free radicals, which can build up in cells and cause damage*
  • The potent antioxidant effect of glutathione helps keep cells running smoothly*

Promotes Detoxification*

Glutathione also helps support healthy liver function.  The highest amounts of glutathione are found in the liver and kidneys, which are responsible for the removal of toxic components. High amounts of glutathione are also found in the brain and lung lining.*

Fortifies Immune System*

Glutathione supports the normal function of the immune system.*

  • Plays a critical role in the proper function of white blood cells, including T cell lymphocytes and the multiplication of lymphocytes (the cells that mediate specific immunity)*
  • Adequate function of white blood cells is essential in mounting an effective immune response

Features:

  • Published, peer-reviewed research demonstrated superior cellular absorption
  • Heat stable, no refrigeration necessary
  • Available in natural watermelon or orange flavor
  • GMO-free
  • Vegan

Patient/Doctor Experiences*

“I really love Tri-Fortify® Orange. Of all the dozens of supplements and meds I take, Tri-Fortify® is by far my favorite. I feel powerful results literally within seconds, every time I take it, I take a teaspoon…  The delicious orange taste mixes well with other liposomal supplements I take.” – Brian B.

“I spent time with Vivian and she had me take a sample of Glutathione gel [Tri-Fortify® Orange]… It had an increasingly positive effect on me. I had a business appt. at 2:00 and I actually felt alive and thinking!!!… The rest of the evening was great….” – patient of V. Kushner

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SKU: 22512354074

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4.4 ★★★★★
Based on 20 reviews
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Product Reviews
W
Verified Purchase
wendy weather
Cuba, US
★★★★★ 5
These are must haves for dog owners!
Size: Large, Color: Pink
These things have saved my sanity! I have two dogs and we use these at least two to three times per week. They are high quality and last thru heavy chewers. We spread peanut butter inside for a quick treat when clipping nails, or make our own mix of Greek yogurt, dry oatmeal, diced carrots, a little pumpkin, and a bit of diced apple, mix it up and freeze it in the Pupsicle mold. That way we have a bunch ready to go and aren’t buying expensive refills. The colors are adorable, the pupsicle is durable, and the dogs LOVE them. FYI - it’s a good idea to use a little olive or avalado oil on the threads when closing them up - it makes life so much easier when screwing then on and off. We throw ours into the dishwasher.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 6, 2026
P
Verified Purchase
professional grade
Massapequa, US
★★★★★ 5
Like unto the Holy Grail of food toys. [I recommend buying the separate treat mold, too.]
Size: Large, Color: Green
So far, I have no complaints. I can see that this toy might not work well for some combinations of dogs and people, but for my two current dogs (blue heeler and small terrier), this thing, plus the treat mold, is GREAT! I love that the dogs get it more or less fully emptied, and it is washable. I love that I can pre-prepare a whole bunch of frozen fillings by using the treat mold (sold separately). Yes, I agree that this is a very expensive item, especially if you buy the treat mold along with the toy. I bought two toys at a very reduced price on Prime day, also bought the treat mold at full price, and consider the combined purchase a great value at this cost. The current price (for the toy) is comparable to the cost of an extra-large Toppl, and I've seen it at a price similar to the current cost of a large Toppl. I checked the current price of the XXL "extreme" Kong I needed to use for one dog, and the current price on a different web site is almost the same as the Woof Pupsicle. To answer questions and issues I've seen mentioned... * My terrier weighs 16 pounds and uses the large toy with no problem. Possibly it is minimally less thoroughly cleaned out, but I'm not positive about that. My only warning would be that you ought to keep track of calories and/or what you put in it because you could potentially give a small dog way too many empty calories from "junk food." * The toy is still usable without the treat mold. Just fill up the solid half of the toy and stick it in the freezer overnight, same as you would do with a Kong, except it takes up less space. * Do introduce it properly, by initially giving it with NON-frozen and sticky food in it. An even more slow, careful, step-wise introduction may be necessary if your dog is a destructo-dog. * The terrier takes about 20 minutes to empty it of frozen canned dog food. That's non-trivial, and I'm not sure why people are complaining. The heeler takes less time (maybe 15 minutes?), but it's still an amount of time that is helpful for me, and this licking activity seems to be especially calming for her (as compared to using the food puzzle toys with kibble). * It initially was extremely difficult to open and close the thing. I was best able to do it with a "light" touch, not pulling and making sure not to press the two surfaces together. After not very long, it became much easier. I didn't need to use oil. If you have trouble getting it closed, it became a lot easier after the solid part was frozen (while the vented part stayed at room temperature). * I agree with others that a larger version might be nice, but a larger version might make dogs more likely to destroy the toy in place of emptying it by focused licking. * I'm not sure that any of these toys are truly indestructible. People are mentioning Kongs. Well, my Kongs have required periodic replacement. They have tooth marks and eventually get "modified" to where pieces might get torn off and consumed. For one dog, I had to upgrade to the XXL-size Extreme (black) version, and she also put tooth marks in that. I own a fortune's worth of Kongs, Toppls, and a couple similar food toys, and they all have their issues. They have holes in them that allow liquid to immediately come out (before freezing occurs). They are bulky and use up a lot of space in the freezer, and the unusual shapes make them non-stackable. For me, Kong toys are time-consuming to fill and difficult to clean. My dogs couldn't get the very end cleaned out without throwing the Kong around (making a big mess), and even then it wasn't fully clean. Some did end up with mold in that part of them. [It looks like new inventions, like plugs (or something like that), may solve some of the problems; I didn't have those.] I mention the other toys only to say that this unique brilliant toy has seeming solved all those problems, and my dogs truly LOVE this toy as well. Be assured, I will update this review if anything changes.
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Reviewed in the United States on July 24, 2023
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Verified Purchase
Matthew Paul
Waukegan, US
★★★★★ 4
Perfect for Our Nervous Rescue Dog
Size: Large, Color: Green
First Impressions I bought the Pupsicle for our new rescue dog who was very nervous whenever we had to leave the house. Right out of the box it felt sturdy and well-made, and I liked that it wasn’t just another cheap chew toy. ⸻ Setup & Ease of Use I went with the premade treat inserts to start, which made it super simple — just pop one in and hand it over. It’s also dishwasher-safe, which is a huge win for me since I don’t want to deal with scrubbing peanut butter out of toys. ⸻ Performance in Real Life She loves it. The Pupsicle has kept her occupied and calm, which has really helped her acclimate to her new home. Instead of pacing or whining when we leave, she settles down with this toy and stays busy. ⸻ Pros & Cons Pros: • Helps reduce anxiety for nervous dogs • Very durable and solid • Easy to clean (dishwasher safe) • Premade inserts make it effortless Cons: • On the heavier side, so probably best for medium+ dogs • Inserts are convenient but add a little extra cost ⸻ Who It’s For Perfect for new dog owners, rescues, or anyone with a dog who needs a healthy distraction when left alone. ⸻ Final Verdict The Pupsicle has made a noticeable difference for our rescue pup. It’s durable, easy to use, and has genuinely helped her feel more at ease in her new environment. Highly recommend.
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Reviewed in the United States on August 24, 2025
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Verified Purchase
taximom
Grantham, US
★★★★★ 3
Dogs love it, hard to open and close
Size: Large, Color: Pink, Size: Large, Color: Pink
My dogs love this toy. It keeps them entertained a long time. Great calming toy for when you leave the house. Only issues is it is very hard to open and close. One of mine I had three people try to open and after fighting with it for about an hour I finally got it opened. Got 2, one a blue and pink one for each of my dogs. The blue is easier than the pink but still hard to do. Just not as bad. Can't close the pink all the way because it is so hard to close. The dog that uses it has trouble getting the stuff out of it. But it doesn't stop her from trying for hours to do so. Does get some teeth marks on it as well if they are aggressive chewer. Tried multiple eatable lubricating substances to try to make it easier but so far nothing fully worked. Aloe Vera has worked the best so far, but not great.
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Reviewed in the United States on February 17, 2026
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Verified Purchase
CS Niles
Phoenix, US
★★★★★ 3
Good in theory, but didn’t fully deliver
Size: Large, Color: Green, Size: Large, Color: Green
My dog falls right on the size cutoff between the small and large Pupsicle. I initially ordered the large since he’s a strong chewer, but he had trouble getting everything out, so I ended up trying the small as well. There are definitely some positives. I think the design is better than a Kong. It stays upright, which makes it less messy. I also really like the mold for making the inserts, instead of having to fill the toy itself and freeze it. That said, there are two major design issues that impacted my experience. First, the all-rubber construction creates a lot of friction when screwing the bottom into the base, especially after repeated use. It gradually became harder to open, to the point where I was using coconut or avocado oil to try to loosen the threads. At one point I even needed a wrench and pliers just to get a better grip. Second, while it’s marketed as dishwasher safe (which I was excited about for cleaning), it seems to dry out the rubber and makes the threading issue worse over time. Unfortunately, mine is now permanently stuck shut and no longer usable. Overall, I like the concept, but the durability and usability issues make this a 3-star product for me. I’d recommend it with caution, especially if you plan to wash it frequently.
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Reviewed in the United States on April 23, 2026

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