NAD Triple Boost™  with NMN - 90 capsules

The Most Complete NAD+ Formula Ever Developed

• Recharges cellular energy at the source*^2,3,5,16,17   
• Supports youthful function in every cell*^{1-3,5–8,13,16} 
• Helps your body repair and renew itself*^1-3  
• Strengthens the systems that decline with age*^1-3,8   
• Backed by the world’s most advanced NAD+ science*

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A Smarter Way to Optimize NAD+*

NAD+ is more than a molecule — it’s the spark behind life itself, driving energy production, cellular repair, and resilience across every system of the body. But true NAD+ support goes beyond simply adding precursors. It requires a comprehensive strategy that:

• Builds NAD+ through multiple molecular entry points*
• Protects NAD+ from depletion and breakdown*
• Transforms NAD+ into usable cellular energy*

That’s the science behind ProHealth’s NAD Triple Boost. Using a systems-based approach, it supports every step of the NAD+ lifecycle, helping replenish what aging reduces and delivering whole-body vitality you can truly feel.*^1-3,6-8

Three Ways to Unlock Your NAD+ Potential

Build: Fuel Every Pathway*

The body builds NAD+ through several pathways. By providing a broad spectrum of precursors, this formula fuels the most important routes of NAD+ synthesis — helping maintain healthy, youthful levels of this vital coenzyme.*

• NMN (Nicotinamide Mononucleotide): A clinically studied vitamin B3 derivative that drives the Salvage Pathway, recycling NAD+ for mitochondrial energy and sirtuin activation.*^2,16,17
• Vitamin B3 (Niacin & Niacinamide): Dual forms that feed both the Preiss–Handler and Salvage Pathways, the body’s main NAD+ production routes.*^7,13
• Tryptophan: An essential amino acid that supports serotonin synthesis while fueling the De Novo Pathway to generate NAD+ from scratch.*^1,2,7
• NMNH (Reduced NMN): A next-generation NAD+ precursor that bypasses rate-limiting steps, producing NAD+ faster and more efficiently.*⁸

Protect: Defend Your NAD+ Stores*

NAD+ can be rapidly depleted by enzymes such as CD38. NAD Triple Boost includes compounds that defend your stores, helping to minimize loss and extend NAD+ availability.*

• Apigenin: A plant flavonoid that supports the preservation of NAD+ by targeting CD38, an enzyme that naturally consumes NAD+.*⁴

Transform: Turn NAD+ Into Energy*

Optimal NAD+ levels are only part of the equation. Your cells must efficiently use NAD+ to power critical enzymes and pathways related to aging and cellular health.* 

• B Vitamins: (including methyl-folate and methyl-B12): Essential cofactors for ATP generation and methylation, important for energy metabolism and the recycling of NAD+ breakdown products.*^9-12  
• Stilbenoids (Resveratrol, Pterostilbene, & Piceatannol): Powerful polyphenol compounds that boost the activity of sirtuins — a family of enzymes that use NAD+ to fuel their activity. By activating sirtuins, these compounds help amplify the benefits of increased NAD+ levels.*^14,15  

Your All-in-One NAD+ System

NAD Triple Boost isn’t just another supplement; it’s a comprehensive system designed to work with your body’s natural biology. By combining multiple proven precursors, plant compounds, and essential cofactors, it supports NAD+ at every stage of its lifecycle. The result is a formula that not only helps restore youthful NAD+ levels but also preserves them and channels them into real cellular energy. It’s a complete, science-driven solution for those who want to stay energized, resilient, and strong as they age.*^{1-3,5-8,13,16,17}

The ProHealth Difference

• Doctor-Formulated: Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*
• Triple Lab Tested: Rigorously tested three times by independent third-party labs to guarantee unmatched potency and purity.
•  Full Transparency: In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle. 
• Manufactured in the USA: Since 1988, we’ve proudly produced our supplements in FDA-regulated, GMP-certified facilities, ensuring the highest quality and safety standards.
• 100-Day Risk-Free Guarantee: We stand behind our products. If you’re not completely satisfied, contact our Santa Barbara, CA office for a full refund—no hassle, no questions asked.

A Word from our Chief Science Officer

“The NAD+ ecosystem isn’t a single switch. It is a dynamic, ever-evolving network of pathways, feedback loops, and cellular compartments that change with age. That’s why NAD Triple Boost was built to go beyond simple replenishment. By targeting multiple control points across the entire NAD+ system, we’re helping the body unlock its full regenerative potential. This is truly a smarter, more complete approach to NAD+ optimization.”

Pioneering Longevity Since 1988

No company offers a broader or more advanced range of NAD+ solutions than ProHealth. From foundational ingredients like NR and NMN to next-generation compounds such as NMNH and Apigenin, our collection spans every major pathway of NAD+ production. With diverse delivery forms, clinically studied ingredients, and formulations that address energy, brain function, metabolism, and longevity, ProHealth stands as the global leader in NAD+ innovation — trusted by researchers, practitioners, and health seekers worldwide.*

Ingredient Info 

• Nicotinamide Mononucleotide (NMN): A clinically studied form of vitamin B3 that supports the NAD+ salvage pathway, helping replenish cellular NAD+ levels efficiently.* 
• Tryptophan: An essential amino acid that feeds the De Novo NAD+ pathway.* 
• Apigenin: A plant-based flavonoid that helps preserve NAD+ levels by targeting CD38, an enzyme known to degrade NAD+ in the body.* 
• B Vitamins: Includes methylated and bioactive B vitamins that support mitochondrial energy production and provide methyl groups crucial for NAD+ metabolism.* 
• Magnesium: A vital cofactor required for enzymatic reactions in NAD+ synthesis and ATP production, supporting optimal cellular energy function.*
•  Resveratrol: A polyphenol that activates sirtuins—NAD+ dependent enzymes linked to longevity, cellular repair, and healthy aging.*
• Pterostilbene: A powerful polyphenol related to resveratrol, known for its superior bioavailability and ability to activate sirtuins, support antioxidant defenses, and promote healthy NAD+ metabolism.* 
• NMNH (Reduced NMN): A next-generation NAD+ precursor that bypasses key rate-limiting steps to support faster, more efficient NAD+ production through an alternative biochemical pathway.* 
• Piceatannol: A naturally occurring stilbenoid that supports healthy inflammation signaling and may complement sirtuin activation and cellular resilience mechanisms.* 

References:

1. Conlon N et al. Biochem Pharmacol. 2022;198:114946.
2. Rajman L et al. Cell Metab. 2018;27(3):529-547.
3. Xie N et al. Signal Transduct Target Ther. 2020;5(1):227.
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5. Membrez M et al. Nat Metab. 2024;6(3):433-447.
6. Nadeeshani H et al. J Adv Res. 2021;37:267-278.
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8. Song Q et al. Adv Nutr. 2023;14(6):1416-1435.
9. Oregon State University - Linus Pauling Institute. Magnesium. Accessed July 26, 2024. https://lpi.oregonstate.edu/mic/minerals/magnesium. 
10. National Institutes of Health. Magnesium Fact Sheet for Health Professionals. Accessed July 26, 2024. https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional.
11. Dominguez LJ et al. Nutrients. 2024;16(4):496.
12. Barbagallo M et al. Magnes Res. 2009;22(4):235-246.
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