SKU: 46987022368

Pterostilbene Pro 250 - 250 mg, 60 capsules - 3 pack

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Description

Pterostilbene Pro 250 - 250 mg, 60 capsules - 3 packPterostilbene is a powerful antioxidant that is similar to, but more bioavailable than resveratrol. Pterostilbene promotes longevity and improves markers associated with heart and brain health. Supports cardiovascular health* Promotes brain cell health* Activates sirtuins to support healthy aging Boosts effectiveness of NMN View Certificate of Analysis Research Supported Benefits: Supports Longevity. Pterostilbene activates longevity genes known as

Pterostilbene is a powerful antioxidant that is similar to, but more bioavailable than resveratrol. Pterostilbene promotes longevity and improves markers associated with heart and brain health.

  • Supports cardiovascular health* 
  • Promotes brain cell health* 
  • Activates sirtuins to support healthy aging 
  • Boosts effectiveness of NMN 

View Certificate of Analysis

Research-Supported Benefits:

Supports Longevity. Pterostilbene activates “longevity genes” known as sirtuins. Research shows that activating sirtuins promotes cellular health and extends lifespan of animals. 1 2 Activating sirtuins aids in DNA repair, promoting cellular stress resistance, regulating autophagy (cellular detoxification) and inflammation. 3

Promotes Heart Health. Research shows that pterostilbene promotes heart health in a variety of ways, one of which is reducing oxidative stress of the heart. 4 Oxidative stress contributes to inflammation and accelerated aging of heart cells. Reducing levels of oxidative stress reduces risk of age-related decline of heart health.

Protects the Aging Brain. Pterostilbene has been shown to reduce neuroinflammation (inflammation of brain cells), reducing oxidative-stress-related damage to brain cells 5. Research shows that neuroinflammation contributes to age-related brain decline symptoms such related to memory and information processing.6

References:

1. Cheng Y, Di S, Fan C, et al. SIRT1 activation by pterostilbene attenuates the skeletal muscle oxidative stress injury and mitochondrial dysfunction induced by ischemia reperfusion injury. Apoptosis. 2016;21(8):905-916. doi:10.1007/s10495-016-1258-x 

2. Lee SH, Lee JH, Lee HY, Min KJ. Sirtuin signaling in cellular senescence and aging. BMB Rep. 2019;52(1):24-34. doi:10.5483/BMBRep.2019.52.1.290 doi:10.5483/BMBRep.2019.52.1.290 

3. Vazquez BN, Thackray JK, Serrano L. Sirtuins and DNA damage repair: SIRT7 comes to play. Nucleus. 2017;8(2):107-115. doi:10.1080/19491034.2016.1264552

4. Kosuru R, Kandula V, Rai U, Prakash S, Xia Z, Singh S. Pterostilbene Decreases Cardiac Oxidative Stress and Inflammation via Activation of AMPK/Nrf2/HO-1 Pathway in Fructose-Fed Diabetic Rats. Cardiovasc Drugs Ther. 2018;32(2):147-163. doi:10.1007/s10557-018-6780-3

5. Park B, Lee YJ. Pterostilbene Improves Stress-Related Behaviors and Partially Reverses Underlying Neuroinflammatory and Hormonal Changes in Stress-Challenged Mice. J Med Food. 2021;24(3):299-309. doi:10.1089/jmf.2020.4766

6. Ahmad MA, Kareem O, Khushtar M, et al. Neuroinflammation: A Potential Risk for Dementia. Int J Mol Sci. 2022;23(2):616. Published 2022 Jan 6. doi:10.3390/ijms23020616

  • Pterostilbene has been shown to activate longevity genes known as sirtuins, which play a critical role in regulating cellular aging. 
  • Sirtuins require NAD+ for fuel, making pterostilbene and NMN a perfect supplement combination to promote longevity. 
  • By activating sirtuins, pterostilbene supports DNA stability and promotes DNA repair. 
  • Pterostilbene’s antioxidant effects promote heart and brain health by reducing oxidative stress and inflammation. 
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
Pterostilbene 250 mg
† Daily Value (DV) not established.
REV.08.25 

  • OTHER INGREDIENTS: Hypromellose (capsule), rice flour.
  • SUGGESTED DAILY USE: Take one (1) capsule 1-2 times per day, preferably with food.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF  CHILDREN. Store in a cool and dry place aer opening.

Clinical-Supported Dosing. ProHealth Longevity’s Pterostilbene Pro 250 contains 250 mg of pterostilbene per serving, a clinically effective dose to promote longevity.

Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.

Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
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SKU: 46987022368

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4.8 ★★★★★
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Lesley
Omaha, US
★★★★★ 5
Hotel quality, budget friendly
Size: King, Style: Light
I’ve only used this for several nights. Overall I’m pretty happy with it, especially for the price. It is soft to the touch and has a nice, smooth feel. It’s lightweight but still provides enough warmth for mild to cool nights. I don’t like feeling weighed down when I sleep, so the light fill is actually a big plus for me. If you’re someone who sleeps hot, this is a solid choice. The corner tabs are super helpful. I paired it with a duvet cover and haven’t had issues with shifting or bunching. It also fits my bed well, though I could see it being a bit short on the sides if you have a very thick mattress. This is a great budget-friendly option and seems like it will be easy to maintain.
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Reviewed in the United States on September 19, 2025
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Chinaza Madu
Draper, US
★★★★★ 5
A Great Comforter for Everyday Use
Size: Full/Queen, Style: All-Season
I absolutely love this comforter! I love the fact it’s machine washable, and it held up really well after the first wash. It fluffed back up nicely, stayed soft, and didn’t lose its shape. It’s not too heavy but still cozy enough to keep you comfortable. For the price, the quality exceeded my expectations, and I am very happy with this purchase. I highly recommend 😊
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Reviewed in the United States on June 4, 2026
L
Verified Purchase
Laurie A. English
Pawtucket, US
★★★★★ 5
Excellent down alternative insert
Size: Full/Queen, Style: All-Season
I purchased this down alternative for my Airbnb because we can easily wash it. I love that it is fluffy and warm and easy to put into the duvet. Price was great as well!!
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Reviewed in the United States on April 19, 2026
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Renee
Bozeman, US
★★★★★ 5
Feels luxury, I approve
Size: King, Style: Warm
I have purchased high end comforters/duvet inserts and this one is somehow my favorite. It's so thick and fluffy. I was going to do the double duvet insert method to create an extra lush bed situation, but honestly it's not needed at all with this comforter! It poofs up wonderfully inside my duvet cover (king duvet, king insert) and it's like heaven. It's very cozy yet airy, and it moves well during the night and does not fee too heavy despite its weight. This thing is definitely on the warm end and probably won't be suitable for Florida summers, but depending on how you set the AC at night it could be fine! The comforter is weighty, it feels like quality, and has a soft fabric. I wouldn't use it without a duvet cover, that's more of an aesthetic choice but I like keeping it clean. The white is very white. Honestly, I will be getting another one simply because I'm so impressed. Definitely no need to drop $300+ dollars elsewhere.
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Reviewed in the United States on October 25, 2025
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Rosalie
Boise, US
★★★★★ 4
ALL SEASON IS TOO WARM!
Size: King, Style: All-Season
I got the King, All Season, to squeeze into a Queen duvet for extra floof and it's sooo cozy. Highly recommend. I redacted 1 star though because although it says All Season, the amount of down in here feels like it's for winter. The first night I used it I woke up dripping in sweat. It's currently March, I live in Los Angeles area, hitting about 75° weather outside rn, but I sleep with AC full blast at night (usually hit about 64 when I wake up). I can't sleep with it, I'll need to buy the "cool" one, and hope that isn't tooo thin. Don't get me wrong, it's a great insert, but holy hell, it's too heckin' warm. I saw someone else mention it and wish I had honed in on their comment. I don't wanna return it as it was used, so I'm stuck with it now. *UPDATE* I am back because I also bought the "Cool" blanket as well after experiencing the heat of the all season and it too is also too hot for me. I've had a duvet before but I guess not filled to the capacity of these blankets. If you're a hot sleeper maybe look elsewhere?
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Reviewed in the United States on March 12, 2026

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