Nicotinamide Riboside Pro Complete - 500 mg NR Hydrogen Malate + 500 mg Trans-Resveratrol + 100 mg TMG per serving, 60 capsules

The Ultimate Longevity Stack*

• Rapidly raises NAD+ levels*^1-9
• Fuels mitochondrial energy production*^2,10,11
• Supports healthy methylation pathways*^1,2,12-14
• Activates sirtuin longevity enzymes*^1,2,6,15-17
• Targets multiple hallmarks of aging*^1,18,19

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Nicotinamide Riboside Pro Complete is a doctor-formulated trio that brings together three clinically-studied longevity ingredients—NR (Nicotinamide Riboside), TMG (Trimethylglycine), and Trans-Resveratrol—for powerful, systems-level support. Together, they drive three essential pathways of healthy aging: NAD+ production, methylation balance, and sirtuin activation. This synergistic design helps maximize the benefits of NAD+ across your entire body.*^1-9,12-17

Why It Works

There’s a reason this formula has been a best-seller since its launch—and why many of the most respected names in longevity science rely on this specific combination. It’s more than a NAD+ booster; it’s a comprehensive longevity regimen that targets aging at its cellular core.*^1-10,12-14

NR (Nicotinamide Riboside): Rebuilds your body’s NAD+ supply*

This next-generation form of NR offers enhanced stability and dual-action support. It helps restore NAD+ levels that decline with age while delivering malate—an essential compound in the Krebs cycle that promotes ATP energy generation and mitochondrial health.*^1-7,18

TMG (Trimethylglycine): Maintains healthy methylation*

Trimethylglycine is an important methyl donor that helps maintain healthy homocysteine levels and supports the clearance of NAD⁺ byproducts like nicotinamide. A well-functioning methylation cycle is essential for sustaining NAD+ metabolism—making TMG a valuable companion to any NAD+ boosting regimen.*^12-14

Trans-Resveratrol: Activates sirtuin longevity enzymes*

This formula includes Veri-te® Trans-Resveratrol—a clinically-studied polyphenol shown to activate sirtuins, a family of NAD+ dependent enzymes that regulate key cellular functions like DNA repair, inflammation response, and metabolic balance. By supporting sirtuin activity, resveratrol helps amplify the benefits of NAD+.*^10,11,16

A Systems-Level Approach to Aging: Supporting All 12 Hallmarks*

Healthy aging isn’t about supporting just one pathway; it requires a systems-based approach that addresses the interconnected processes that naturally decline over time. NAD+ sits at the center of this physiological web, helping fuel enzymes involved in DNA repair (like PARPs), gene expression (via sirtuins), energy production, and the body’s responses to oxidative stress and inflammation. As NAD+ declines—by up to 50% by midlife—these core functions begin to break down, accelerating aging at the cellular level.^3,20,21

By replenishing NAD+ and supporting its broader metabolic ecosystem, Nicotinamide Riboside Pro Complete helps reactivate key defense systems that impact all 12 hallmarks of aging—from genomic stability and mitochondrial function to inflammation and cellular communication. It’s a systems-based strategy for healthier aging from the inside out.*^1-3,10,20,21

The ProHealth Difference

• Doctor-Formulated: Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*
• Triple Lab Tested: Rigorously tested three times by independent third-party labs to guarantee unmatched potency and purity.
•  Full Transparency: In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle. 
• Manufactured in the USA: Since 1988, we’ve proudly produced our supplements in FDA-regulated, GMP-certified facilities, ensuring the highest quality and safety standards.
• 100-Day Risk-Free Guarantee: We stand behind our products. If you’re not completely satisfied, contact our Santa Barbara, CA office for a full refund—no hassle, no questions asked.

A Word from our Chief Science Officer

“NR Pro Complete represents where NAD+ science is headed. We’ve combined a next-generation form of Nicotinamide Riboside with clinically- studied support for sirtuin activation and methylation balance—creating a formula that doesn’t just rebuild NAD+, but helps sustain and amplify its effects throughout the body. This is the same protocol trusted by leading researchers and experts in the field of longevity. It’s more than a supplement—it’s a daily blueprint for healthy aging.”

Ingredient Info

• Nicotinamide Riboside:: A vitamin B3 derivative and essential precursor in the NAD+ production pathway.*
• Trans-Resveratrol:: A powerful polyphenol found in red grapes, clinically studied for its ability to activate SIRT1.*
• Trimethylglycine: A natural methyl donor that supports healthy homocysteine levels and helps maintain efficient NAD⁺ metabolism.*

References:

1. Orr Me et al. GeroScience. 2024;46(1):665-682.
2. Nascimento EBM et al. J Clin Endocrinol Metab. 2021;106(5):1437-1447.
3. Vreones M et al. Aging Cell. 2023;22(1):e13754.
4. Elhassan YS et al. Cell Rep. 2019;28(7):1717-1728.e6.
5.  Dolopikou CF et al. Eur J Nutr. 2020;59(2):505-515.
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15. Dzator JSA et al. IBRO Neurosci Rep. 2023;15:310-319.
16. Thaung Zaw JJ et al. Menopause. 2021;28(1):40-49.
17. Bartra C et al. Antioxidants. 2024;13(2):177.
18. Mehmel M et al. Nutrients. 2020;12(6):1616.
19. Zhou DD et al. Oxid Med Cell Longev. 2021;2021:9932218.
20. Conlon N and Ford D. Biochem Pharmacol. 2022;198:114946.
21. Janssens GE et al. Nat Aging. 2022;2(3):254-263.