SKU: 42771102852

Pacific Blue Mouse Anti-Mouse CX3CR1 Antibody (S-R597)

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Description

Pacific Blue Mouse Anti-Mouse CX3CR1 Antibody (S-R597)Product Specification Host Mouse Antigen CX3CR1 Synonyms CX3C chemokine receptor 1; C X3 C CKR 1; mCX3CR1; Fractalkine receptor Location Cell membrane Accession Q9Z0D9 Clone Number S R597 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein A Concentration 0. 5 mg ml Conjugation Pacific Blue Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability

Product Specification


Host Mouse
Antigen CX3CR1
Synonyms CX3C chemokine receptor 1; C-X3-C CKR-1; mCX3CR1; Fractalkine receptor
Location Cell membrane
Accession Q9Z0D9
Clone Number S-R597
Antibody Type Mouse mAb
Isotype IgG2a,k
Application FCM
Reactivity Ms
Positive Sample BALB/c mouse splenocytes
Purification Protein A
Concentration 0.5 mg/ml
Conjugation Pacific Blue
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 1μg per million cells in 100μl volume Ms

Background

CX3CR1 is a seven-transmembrane G-protein-coupled receptor expressed on monocytes, macrophages, dendritic cells, microglia and tissue-patrolling lymphocytes that serves as the exclusive receptor for the unique membrane-tethered or soluble chemokine CX3CL1 (fractalkine), thereby orchestrating leukocyte adhesion, chemotaxis and survival during development, homeostasis, viral and bacterial infections, inflammatory diseases such as atherosclerosis and rheumatoid arthritis, neuroinflammatory conditions including Alzheimer’s disease, and tumor progression or metastasis, while also acting as a co-receptor for respiratory syncytial virus entry into airway epithelium and modulating antiviral immunity via IL-10 induction.

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SKU: 42771102852

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4.1 ★★★★★
Based on 9 reviews
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F
Verified Purchase
Forrest F.
Houston, US
★★★★★ 5
The history is unpleasant and therefore worth knowing.
It's a wonderfully enlightening history of how European explorers visited, settled in, conquered, and exploited other continents with unparalleled cruelty in the name of power, greed, and their "loving" religion that brought them misery, exploitation and, all too often, abject slavery.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 9, 2025
M
Verified Purchase
Marianne Mountain Dawn Scofield
Lexington, US
★★★★★ 5
Wonderful History Lessons
I ordered this book to use for a college paper I was writing and found it fascinating. I enjoyed the content and learned much from it. The history is written in a manner that for those people that either don't read much or don't like to read (yes, there are a few people out there), it will draw you in and make you question the history lessons we suffered through in high school.
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Reviewed in the United States on January 11, 2013
A
Verified Purchase
Amazon Customer
Lake Worth, US
★★★★★ 5
Excellent and Eye Opening
Where but in America could white men kill 2,ooo,ooo people to prove they are more civilized ?
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 16, 2017
K
Verified Purchase
Ken Kardash
New York, US
★★★★★ 4
Rediscovering America
This is an eye-opening, scholarly rebuttal to common perceptions about native American society before and after the European invasion. Ronald Wright makes no secret of his bias in favor of the people who were here first; in fact, he enhances the impact of what for many will be new information by presenting this extraordinary history from the point of view of the conquered. He also makes clear how large a part of the conquest was due to immune system rather than military deficiencies: if smallpox and other diseases had not done killed most of the native population, the facts recounted here suggest that history, particularly in South America, may have evolved quite differently. In undertaking the massive task of recounting the invasion of all of the Americas, some selectivity is inevitable. Wright has chosen to focus on the story of five distinct native groups: Aztec, Maya, Inca, Cherokee and Iroquois. He then arbitrarily subdivides the story into three consecutive time periods: Conquest, Resistance and Rebirth. After the physical and political annihilation recounted in the first two sections, the title of the third may seem overly optimistic, particularly for the Guatemalan Maya. However, the concluding tone is more conciliatory and hopeful than mournful, particularly in the Afterword that updates matters to 2005, 13 years after the original publication date. The astounding amount of research involved in producing this admittedly selective overview is well-indexed and annotated. My only quibble is that Wright, obviously an expert in the field of native culture, sometimes borders on the compulsive in matters of linguistic authenticity. I did not buy this book to learn ancient native languages, let alone their pronunciation, and at times I found the inclusion of such trivia distracted from rather than enhanced the otherwise convincing scholarship. This obsession with accuracy is commendable, but after getting it out of his system in the Author's note, his amazing narrative would have been no less compelling if he stuck to the language of his contemporary audience. Also, for an author who has settled in British Columbia, it is strangely disappointing that the rich history of the Pacific Northwest coastal natives was not among those he chose to examine. I had read Charles Mann's "1491" prior to this book and found it primed my interest in the subject; both are excellent introductions to the reality of pre-Columbian American societies, but Stolen Continents provides more of a historical context for what has become of them.
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Reviewed in the United States on October 13, 2008
I
Verified Purchase
Irving Dozier
Dallas, US
★★★★★ 5
... true things that really went on to know very great
Format: Hardcover
lots of true things that really went on to know very great book
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on October 13, 2016

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