Pay in installments of $28.75 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 23 - Jul 28
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Alexa Fluor® 488 Mouse Anti-Human CD160 Antibody (S-3866)Product Specification Host Mouse Antigen CD160 Synonyms CD160 antigen; Natural killer cell receptor BY55; BY55 Location Cell membrane Accession O95971 Clone Number S 3866 Antibody Type Mouse mAb Isotype IgM,k Application FCM Reactivity Hu Positive Sample Human PBMC Concentration 0. 2 mg ml Conjugation Alexa Fluor 488 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of receipt
Product Specification
| Host | Mouse |
| Antigen | CD160 |
| Synonyms | CD160 antigen; Natural killer cell receptor BY55; BY55 |
| Location | Cell membrane |
| Accession | O95971 |
| Clone Number | S-3866 |
| Antibody Type | Mouse mAb |
| Isotype | IgM,k |
| Application | FCM |
| Reactivity | Hu |
| Positive Sample | Human PBMC |
| Concentration | 0.2 mg/ml |
| Conjugation | Alexa Fluor® 488 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Hu |
Background
CD160 is a glycosylphosphatidylinositol-anchored cell surface receptor of the immunoglobulin superfamily, expressed on subsets of CD4⁺ and CD8⁺ T cells, γδ T cells, NK cells and NKT cells, that binds classical and non-classical MHC-I molecules (HLA-C, -A, -E, -F) and herpesvirus entry mediator (HVEM) to deliver potent inhibitory or activating signals depending on cellular context; engagement on CD8⁺ T cells triggers PI3K-dependent survival and cytotoxic granule release, whereas on NK cells it enhances cytotoxicity and IFN-γ production, and its soluble form (sCD160) generated by metalloprotease shedding acts as a decoy receptor that limits angiogenesis and tumor growth, making CD160 a key checkpoint regulator of antiviral, antitumor and autoimmune responses.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy